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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PTPRO
All Species:
4.55
Human Site:
S1177
Identified Species:
12.5
UniProt:
Q16827
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16827
NP_002839.1
1216
138344
S1177
E
M
R
S
Y
R
M
S
M
V
Q
T
E
E
Q
Chimpanzee
Pan troglodytes
XP_509219
1996
223893
H1944
D
L
R
L
H
R
V
H
M
V
Q
T
E
C
Q
Rhesus Macaque
Macaca mulatta
XP_001117455
1997
224328
H1945
D
L
R
L
H
R
V
H
M
V
Q
T
E
C
Q
Dog
Lupus familis
XP_543791
1450
163713
S1411
E
M
R
S
Y
R
M
S
M
V
Q
T
E
E
Q
Cat
Felis silvestris
Mouse
Mus musculus
B2RU80
1998
224477
H1946
D
L
R
L
H
R
V
H
M
V
Q
T
E
C
Q
Rat
Rattus norvegicus
O88488
2302
256806
C2244
E
L
R
S
E
R
M
C
M
V
Q
N
L
A
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512269
2148
240953
H2096
D
L
R
L
H
R
V
H
M
V
Q
T
E
C
Q
Chicken
Gallus gallus
Q9W6V5
1406
154195
L1349
D
L
R
M
H
R
P
L
M
V
Q
T
E
D
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P35992
1631
185062
W1509
A
M
R
K
E
R
V
W
M
V
Q
T
E
Q
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
23.2
23.2
81.5
N.A.
22.8
21.4
N.A.
22.4
22.8
N.A.
N.A.
N.A.
22.6
N.A.
N.A.
N.A.
Protein Similarity:
100
37.6
37.4
83
N.A.
37.3
34.1
N.A.
36.5
41
N.A.
N.A.
N.A.
38.5
N.A.
N.A.
N.A.
P-Site Identity:
100
53.3
53.3
100
N.A.
53.3
60
N.A.
53.3
53.3
N.A.
N.A.
N.A.
60
N.A.
N.A.
N.A.
P-Site Similarity:
100
80
80
100
N.A.
80
66.6
N.A.
80
80
N.A.
N.A.
N.A.
73.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% A
% Cys:
0
0
0
0
0
0
0
12
0
0
0
0
0
45
0
% C
% Asp:
56
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% D
% Glu:
34
0
0
0
23
0
0
0
0
0
0
0
89
23
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
56
0
0
45
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
67
0
45
0
0
0
12
0
0
0
0
12
0
0
% L
% Met:
0
34
0
12
0
0
34
0
100
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% N
% Pro:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
100
0
0
12
100
% Q
% Arg:
0
0
100
0
0
100
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
34
0
0
0
23
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
89
0
0
0
% T
% Val:
0
0
0
0
0
0
56
0
0
100
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
23
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _